Ancona is a city and a seaport in the Marche a region of central Italy population 101 909 (2005). Ancona is situated on the Adriatic Sea and is the center of the province of Ancona and the capital of the region. The city is located 280 km northeast of Rome. The town is finely situated on and between the slopes of the two extremities of the promontory of Monte Conero Monte Astagno occupied by the citadel and Monte Guasco on which the Duomo stands (150 m).